The Science
Behind HANS™
Hans is built with a simple, purposeful formula. Every ingredient has a role, and nothing is added without reason.
A New Standard in Dog Wellness
For decades, canine health has ignored hormone health in dogs. Hans is the first daily wellness chew designed to restore that foundation, applying decades of research from human hormone science to the dogs we call family.
Hormone loss is the #1 overlooked driver of premature aging in dogs.
Spay and neuter can remove up to 90% of a dog’s natural hormones.
When hormones decline, everything declines. Strength weakens, energy fades, and recovery slows, because hormones control how the body repairs, moves, and stays strong.
When hormones are protected, true wellness begins.
Hormones Are the Foundation of Health
In both humans and dogs, hormones regulate strength, recovery, metabolism, mobility, mood, and the pace of healthy aging. They are the body’s natural signals, keeping every system in balance. When they decline, every part of health feels the impact.
Early Signs to Look For
The earliest signs of imbalance show subtle shifts in your dog’s energy, movement, and mood - especially as they age or lose hormone production.
Lower Daily Energy
Stiffness + Slower Mobility
Mood + Behavior Changes
Weight Gain + Muscle Loss
Noticeable Changes With Daily Support
With consistent daily support, dogs experience steadier energy, smoother movement, and a more balanced sense of well-being.
More Steady, Noticeable Energy
Smoother, More Comfortable Movement
More Balanced Behavior
Healthier Weight + Better Muscle Support
What's in HANS™
The first daily hormone support chew for dogs, powered by natural growth factors that help restore your dog's natural balance.
Every chew is built to stop aging before it starts, restoring what food and exercise can't.
HANS™ Ingredients Studies
Velvet antler supports joint health and mobility through naturally occurring compounds such as chondroitin sulfate, glucosamine, and collagen peptides that help maintain cartilage structure and reduce inflammation.
Research indicates that velvet antler supplementation improves endurance and post-exercise recovery by stimulating muscle repair and reducing fatigue. Its bioactive components aid in oxygen utilization and nutrient delivery, helping restore physical energy and resilience.
Studies:
Allen M, et al. Elk velvet antler improves joint function in patients with arthritis. Phytother Res. 2008.
Moreau M, Dupuis J, Bonneau NH, Lecuyer M. Clinical evaluation of a powder of quality elk velvet antler for the treatment of osteoarthrosis in dogs. Can Vet J. 2004;45(2):133–139.
Gupta RC, et al. Therapeutic efficacy of deer antler velvet in osteoarthritis models. J Orthop Res. 2022.
Church JS, et al. Bioactive components of velvet antlers and their pharmacological properties. J Ethnopharmacol. 2003.
Wu F, et al. Effect of velvet antler polypeptides on anti-inflammatory response and cartilage regeneration. Int J Mol Sci. 2019.
Wang B, et al. Deer antler polypeptide promotes chondrocyte proliferation and cartilage repair. J Ethnopharmacol. 2018.
Sunwoo HH, et al. Anti-inflammatory effects of velvet antler on joint tissue recovery. Biol Pharm Bull. 1998.
Velvet antler naturally contains endocrine-active growth factors such as IGF-1 and TGF-β, which help maintain healthy hormone signaling and metabolism.
Research shows that velvet antler supplementation supports endocrine balance by increasing circulating levels of IGF-1 and related compounds that regulate metabolism, tissue regeneration, and energy utilization. Studies have observed improved vitality, muscle tone, and recovery in subjects receiving velvet antler extracts compared to controls.
Studies:
Church JS, et al. Bioactive components of velvet antlers and their pharmacological properties. J Ethnopharmacol. 2003.
Sunwoo HH, et al. Effects of deer antler extracts on endocrine and metabolic activity. Biol Pharm Bull. 1997.
Suttie JM, et al. Role of IGF-1 in antler growth and regeneration. J Endocrinol. 1994.
Gupta RC, et al. Therapeutic efficacy of deer antler velvet on metabolic recovery. J Orthop Res. 2022.
Li C, et al. Growth factor expression and regulation in regenerating deer antlers. Dev Dyn. 1999.
Lee NK, et al. Identification of multiple steroid hormones present in velvet antler. Anal Bioanal Chem. 2019.
Velvet antler is rich in amino acids, peptides, and growth factors that promote cellular energy and recovery following stress or exertion.
Research indicates that velvet antler supplementation improves endurance and post-exercise recovery by stimulating muscle repair and reducing fatigue. Its bioactive components aid in oxygen utilization and nutrient delivery, helping restore physical energy and resilience.
Studies:
Sleivert G, et al. The effect of elk velvet antler supplementation in elite athletes. Int J Sport Nutr Exerc Metab. 2003.
Suttie JM, et al. Role of IGF-1 in regeneration and recovery. J Endocrinol. 1994.
Gupta RC, et al. Anabolic and performance effects of deer antler velvet. J Anim Sci. 2022.
Sunwoo HH, et al. Biological activities of deer antler extracts related to physical performance. Biol Pharm Bull. 1997.
Li X, et al. Velvet antler peptide enhances muscle regeneration and reduces fatigue in mice. Front Pharmacol. 2020.
Zhang Y, et al. Effects of velvet antler supplementation on exercise recovery and antioxidant activity. Nutrients. 2021.
Syrotuik D, et al. Effects of elk velvet antler on strength, endurance, and hormonal responses. J Strength Cond Res. 2005.
Velvet antler supports mood balance through its influence on hormonal signaling and stress-regulating pathways within the endocrine system.
Studies suggest that compounds in velvet antler modulate the hypothalamic-pituitary-adrenal (HPA) axis, helping stabilize mood and reduce stress responses. Enhanced energy metabolism and endocrine support further contribute to improved emotional stability and overall demeanor.
Studies:
Gupta RC, et al. Neuroendocrine benefits of deer antler velvet in stress modulation. J Vet Pharmacol Ther. 2021.
Church JS, et al. Bioactive growth factors in velvet antler and their hormonal effects. J Ethnopharmacol. 2003.
Yang Q, et al. Antler polypeptides improve cognition and neuronal survival in animal models. Neurochem Res. 2020.
Kim S, et al. Neuroprotective and stress-modulating effects of velvet antler in rats. Neurosci Lett. 2015.
Zhao X, et al. Antler polypeptide effects on anxiety and mood through hypothalamic regulation. Life Sci. 2017.
Velvet antler supports healthy aging by helping maintain cellular regeneration, hormonal balance, and musculoskeletal health.
Research shows velvet antler may delay age-related declines in muscle mass, bone density, and energy levels by restoring essential growth factors and promoting protein synthesis. These mechanisms parallel anti-aging strategies seen in human wellness approaches targeting hormone health and tissue repair.
Studies:
Sunwoo HH, et al. Anti-aging properties of deer antler extracts in mammalian models. Biol Pharm Bull. 1997.
Gupta RC, et al. Deer antler velvet supplementation and age-related biomarkers. J Orthop Res. 2022.
Suttie JM, et al. IGF-1 mediated tissue regeneration and age modulation. J Endocrinol. 1994.
Church JS, et al. Bioactive components of velvet antlers and their pharmacological properties. J Ethnopharmacol. 2003.
Zhang H, et al. Protective effects of velvet antler polypeptides on oxidative stress and aging markers. J Tradit Chin Med. 2012.
Li C, et al. Molecular mechanisms of antler regeneration and implications for aging biology. Regen Med. 2009.
